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When the therapeutic treatment of Tβ4 was administered after EAE symptoms’ onset instead of on the day of PLP immunization, functional outcomes revealed that this Tβ4 treatment approach evoked significant functional benefit (Zhang et al., 2016a), and concurrently increased OLs in the demyelinating CNS

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• Biological Durability: The peptide's immediate interaction with transcription factors like c-Fos, c-Jun, and Egr-1 allows for angiogenic and anti-inflammatory processes that far outlast the physical presence of the molecule