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The foundational study is a 2014 Nature paper showing that knocking down the NNMT gene protected against diet induced obesity in mice (PMID 24717514)

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10.1371/journal.pone.0076654 [DOI] [PMC free article] [PubMed] 24.Soares MO, Dumville JC, Ades AE, Welton NJ (2014) Treatment comparisons for decision making: facing the problems of sparse and few data

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