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This is often when the first measurable visible changes begin to emerge

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Symptoms that should prompt a test: Persistent fatigue that sleep does not fix Brain fog, poor concentration, or noticeable memory lapses Tingling, numbness, or pins-and-needles in hands or feet Irritability, low mood, or unusual anxiety Pale skin, breathlessness on mild exertion, or a rapid heartbeat A sore, smooth, or beefy-red tongue Balance problems or unsteadiness Do not wait this one out