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Published in Neuroscience Gabrielle Ahern and 4 others Alzheimer’s disease (AD) is renowned as one of the most maleficent neurodegenerative disorders and is a major cause of dementia that slowly destroys the daily life of afflicted individuals

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We first elucidate the intricate pathophysiological mechanisms linking hyperuricemia, monosodium urate (MSU) crystal deposition, NLRP3 inflammasome activation, and chronic inflammation